GHK-Cu copper peptide

GHK-Cu copper peptide occurs naturally in the human body in the blood plasma. Its structure includes a copper molecule and three amino acid residues of L-glycine, L-histidine and L-lysine. It was discovered in 1973 by the biochemist Dr Loren Pickart, and the first studies looked at the properties of the peptide in accelerating wound healing.

As research progressed, the ability of the peptide to improve the appearance of the skin was demonstrated. In one study, women with mild to severe signs of aging regularly applied a cream containing GHK-Cu to their facial skin. The effects were brilliant. Among the participants of the study, one could observe increasing the density and thickness of the skin, reducing its laxity, smoothing fine lines, reducing the depth of furrows and improving the skin tone [1]. Another study compared the effect of a cream enriched with GHK-Cu with creams containing retinoic acid and vitamin C. As many as 70% of the study participants observed better effects after using the GHK-Cu cream. The ladies declared that their skin had a uniform color, it became firmer, more elastic and elastic. Small wrinkles have been smoothed out, and deep furrows have become significantly shallower. Histopathological studies confirmed that GHK-Cu strongly stimulated the multiplication of keratinocytes [2].

GHK-Cu peptide increases collagen production, prevents photoaging, improves elasticity and evens skin tone. Supports the reduction of wrinkles, increases skin density and thickness. It is non-toxic and non-irritating to the skin.


1. Leyden J., Stephens T., Finkey M., Appa Y., Barkovic S. Skin Care Benefits of Copper Peptide Containing Facial Cream; Proceedings of the American Academy of Dermatology 60th Annual Meeting; New Orleans, LA, USA. 22–27 February 2002; p. 68.

2. Finkley M., Appa Y., Bhandarkar S. Copper Peptide and Skin. In: Elsner P., Maibach H., editors. Cosmeceuticals and Active Cosmetics: Drugs vs. Cosmetics.Marcel Dekker; New York, NY, USA: 2005. pp. 549–563.


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